Massachusetts Institute of Technology MIT OpenCoursewareCambridge, Massachusetts, US,

August 25, 2008

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Teachers and students can use these practice problems and solutions to help reinforce what's been covered.

Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel, 7.012 Introduction to Biology, Fall 2004. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA

Prof. Tyler Jacks, Prof. Hazel Sive, 7.013 Introductory Biology, Spring 2006. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA

Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke, 7.014 Introductory Biology, Spring 2005. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA

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Table of Contents

- Genotype and Phenotype Practice Problems
- Central Dogma Practice Problem
- Pedigree Practice Problem I
- Pedigree Practice Problem II
- Recombination and Linkage Practice Problem I
- Recombination and Linkage Practice Problem II
- Sex Linkage Practice Problem
- Mendelian Genetics Practice Problems
- Pedigrees and Genetic Linkage Practice Problems
- Diploid Genetics Practice Problem
- Recombination – Chromosomes Practice Problem
- Pedigrees Practice Problem

Teachers and students can use these practice problems and solutions to help reinforce what's been covered.

Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel, 7.012 Introduction to Biology, Fall 2004. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA

Prof. Tyler Jacks, Prof. Hazel Sive, 7.013 Introductory Biology, Spring 2006. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA

Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke, 7.014 Introductory Biology, Spring 2005. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA

http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc

http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

Introduction to Biology Practice Problems 4 and 5 (and their solution) cover variations on modes of inheritance-co-dominance and epistasis.

Course: 7.012 Introduction to Biology, Fall 2004 Instructors: Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel

Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel, 7.012 Introduction to Biology, Fall 2004. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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Introduction to Biology Practice Problem 2 (and its solution) covers transcription and translation of a given gene and DNA mutations that affect the protein product.

Course: 7.012 Introduction to Biology, Fall 2004 Instructors: Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel

Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel, 7.012 Introduction to Biology, Fall 2004. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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Introductory Biology Practice Problem 1 (and its solution) covers the use family pedigree to predict the mode of inheritance.

Course: 7.013 Introductory Biology, Spring 2006 Instructors: Prof. Tyler Jacks, Prof. Hazel Sive

Prof. Tyler Jacks, Prof. Hazel Sive, 7.013 Introductory Biology, Spring 2006. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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Introductory Biology Practice Problem 2 (and its solution) covers the use pedigree to predict the mode and probability of inheritance.

Course: 7.013 Introductory Biology, Spring 2006 Instructors: Prof. Tyler Jacks, Prof. Hazel Sive

Prof. Tyler Jacks, Prof. Hazel Sive, 7.013 Introductory Biology, Spring 2006. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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Introductory Biology Practice Problem 1 (and its solution) covers mono- and dihybrid crosses to determine mode of inheritance and linkage of two traits.

Course: 7.014 Introductory Biology, Spring 2005 Instructors: Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke

Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke, 7.014 Introductory Biology, Spring 2005. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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Introductory Biology Practice Problem 2 (and its solution) covers characteristics of linked genes and calculation of recombination frequencies.

Course: 7.014 Introductory Biology, Spring 2005 Instructors: Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke

Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke, 7.014 Introductory Biology, Spring 2005. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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Introductory Biology Practice Problem 3 (and its solution) covers how to determine mode of inheritance based on pedigrees and how to calculate the probability of inheriting a disease or being a carrier.

Course: 7.014 Introductory Biology, Spring 2005 Instructors: Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke

Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke, 7.014 Introductory Biology, Spring 2005. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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Introduction to Biology problems (and their solutions) cover one and two trait crosses that demonstrate simple Mendelian genetics as well as codominance and lethal phenotypes.

Course: 7.012 Introduction to Biology, Fall 2004 Instructors: Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel

Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel, 7.012 Introduction to Biology, Fall 2004. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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Introduction to Biology Practice Problem I and II (and their solutions) cover pedigrees of blood groups and two linked traits. Course: 7.012 Introduction to Biology, Fall 2004 Instructors: Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel

Prof. Eric Lander, Prof. Robert Weinberg, Dr. Claudette Gardel, 7.012 Introduction to Biology, Fall 2004. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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Introductory Biology Practice Problem A (and its solutions) cover how to determine genotypes and modes of inheritance based on phenotypes of several crosses.Course: 7.014 Introductory Biology, Spring 2005 Instructors: Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke

Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke, 7.014 Introductory Biology, Spring 2005. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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Introductory Biology Practice Problem A (and its solution) covers the Chromosomal Theory of Inheritance, sexual reproduction, and chromosomal recombination.Course: 7.014 Introductory Biology, Spring 2005 Instructors: Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke

Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke, 7.014 Introductory Biology, Spring 2005. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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Introductory Biology Practice Problem B (and its solution) covers how human pedigrees are used to predict the mode of inheritance.Course: 7.014 Introductory Biology, Spring 2005 Instructors: Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke

Prof. Penny Chisholm, Prof. Graham Walker, Dr. Julia Khodor, Dr. Michelle Mischke, 7.014 Introductory Biology, Spring 2005. (Massachusetts Institute of Technology: MIT OpenCourseWare), http://ocw.mit.edu (Accessed October 1, 2008). License: Creative Commons BY-NC-SA http://ocw.mit.edu/OcwWeb/web/terms/terms/index.htm#cc http://creativecommons.org/licenses/by-nc-sa/3.0/us/legalcode

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