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Other

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Access to the article is free, however registration and sign-in are required. Diffusion of the membrane-fusion protein syntaxin in cell membranes can be explained by a simple model of attraction and repulsion. Sieber, Lang, and co-workers refreshingly turn our attention back to the problem of simple diffusion and clustering of proteins in fluid membranes. They show that the clustering of syntaxin 1 in the plasma membrane of neuroendocrine PC12 cells can be described by a simple physical model. The work is particularly notable because of the importance of syntaxin 1 in the docking and fusion of secretory vesicles to allow external release of their contents (exocytosis).

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      Keywords:

      NSDL,NSDL_SetSpec_BEN,oai:nsdl.org:2200/20110722022845674T,syntaxin clusters,exocytosis,SNARE proteins

      Language:

      English

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      Public - Available to anyone

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      Creative Commons Attribution Non-Commercial Share Alike

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