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Other

Description:

Access to the article is free, however registration and sign-in are required. The action of release factors on ribosomes has now been clarified by crystallography. Two papers—one by Weixlbaumer et al. on page 953 of this issue (1), and the other by Laurberg et al. in Nature (2)—now report crystal structures that shed light on how translation is terminated and how the finished protein is released from the ribosome. The studies investigate two closely related proteins called release factors that respond to different stop codons (nucleotide sequences in mRNA that signal termination of translation) in bacteria.

Subjects:

  • Mathematics > General

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    Keywords:

    oai:nsdl.org:2200/20110722022728356T,NSDL,NSDL_SetSpec_BEN,termination of protein synthesis,release factors,Mathematics,translation

    Language:

    English

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    Public - Available to anyone

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    Creative Commons Attribution Non-Commercial Share Alike

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