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Access to the article is free, however registration and sign-in are required. The structure of a transport protein for divalent metal cations sheds light on how metal concentrations in the cell are regulated. Divalent metal cations are essential for all living cells. For example, Mg2+ stabilizes the phosphates in adenosine triphosphate (ATP), and Zn2+ is required for transcription, immune functions, and neurotransmission. On page 1746 of this issue, Lu and Fu report the structure of a zinc transport protein that elucidates how the zinc concentration of the cell is controlled.
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