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Access to the article is free, however registration and sign-in are required. Permeating throughout a eukaryotic cell is a lattice of filamentous tracks called microtubules, upon which molecular motors travel, moving cargo about. In this transport system, the molecular motor kinesin-1 carries relatively large loads (molecular complexes, membranous vesicles, and organelles), its motion powered by the energy liberated from hydrolyzing adenosine triphosphate (ATP) (1). A mechanism that controls the stepwise movement of the molecular motor along a filamentous microtubule track in the cell does not seem to require the track itself.
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