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Access to the article is free, however registration and sign-in are required. In the area of systems biology, networks of interacting proteins have been explored as models for understanding cellular processes. Many of these networks exhibit a "small world" property, meaning that a connection can be established between any two elements of the network by following only a small number of links. This is due in part to the presence of hubs, which are elements connected to many other elements in the network. Kim et al. add a new chapter to the analysis of hubs in protein interaction networks, clarifying some previously murky issues about how they operate in the cell and how they may have evolved.

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      Keywords:

      protein hubs,NSDL,NSDL_SetSpec_BEN,cellular networks,systems biology,Life Science,small world property,oai:nsdl.org:2200/20110722030910804T

      Language:

      English

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      Public - Available to anyone

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      Creative Commons Attribution Non-Commercial Share Alike

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