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Other

Description:

Access to the article is free, however registration and sign-in are required. Many mammalian cells have indentations in the plasma membrane called caveolae, but exactly what these flask-shaped pits do remains unclear. In a Perspective, Parton discusses the characteristics of caveolin-1-deficient mice that lack caveolae (Drab et al.). The mice are fertile and seem healthy but show cardiovascular defects, suggesting that caveolae may be important in nitric oxide signaling and cellular proliferation.

Subjects:

  • Mathematics > General

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    Keywords:

    oai:nsdl.org:2200/20110722030342474T,NSDL,NSDL_SetSpec_BEN,lipid rafts,regulation,knockout mice,Life Science,Mathematics,caveolins,plasma membrane

    Language:

    English

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    Public - Available to anyone

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