Type:

Other

Description:

The molecular mechanisms underlying Ca2+ entry into sperm are now much more well defined thanks to direct recordings of mature sperm cells. This article reviews the function of a sperm-specific ion channel, CatSper. CatSpers have a clearly defined function in sperm's hyperactivated motility and are essential for male fertility. We propose that physiological stimuli such as zona pellucida and cyclic nucleotides induce Ca2+ entry through CatSper channels instead of acting on CaV and CNG channels as previously thought.

Subjects:

  • Education > General

Education Levels:

    Keywords:

    Education,NSDL,Fertilization,Physics,NSDL_SetSpec_BEN,Sperm,Calcium,oai:nsdl.org:2200/20110722024500764T,Signaling,Life Science,Teacher-centered/traditional instruction,Tutorial or self-directed instruction,Ion channel,Physiology,Student-centered instruction

    Language:

    English

    Access Privileges:

    Public - Available to anyone

    License Deed:

    Creative Commons Attribution Non-Commercial Share Alike

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