This 47-page Practice Guide from the Institute of Education Sciences provides K-12 teachers with specific evidence-based recommendations that can be carried out in the classroom without requiring systemic change. To encourage girls to consider careers in math and science, the guide addresses girls' beliefs about their abilities, the development of their interests in these topics, and building associated skills. The document addresses potential roadblocks for each recommendation as well as possible solutions. Coaches, counselors, and principals may also find the guide useful. It includes an extensive list of references. This Guide supports a companion Doing What Works website, Encouraging Girls in Math and Science (cataloged separately).