Type:

Other

Description:

Etsuko Uno and colleagues at the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia, explain Burnet's clonal selection theory in an animation of the body's response to Streptococcus pyogenes, the bacterium that causes strep throat. Proteins from the invader enter the lymph node and grab the attention of one of billions of B cells. That B cell then clones itself thousands of times and sends antibodies via the bloodstream to the infection site. There, the antibodies bind to the strep bacteria, acting as a red flag that alerts other immune system cells to destroy the infectious agent. "We hope that the animation will pique people's interest in how the immune system works and that they will appreciate the impact of Burnet's clonal selection theory on our understanding of the immune system," Uno says.

Subjects:

  • Education > General

Education Levels:

    Keywords:

    antibodies,NSDL,lymphatic network,clonal selection,NSDL_SetSpec_BEN,Undergraduate upper division 15-16,High school upper division 11-12,immunolgy,membrane receptor,oai:nsdl.org:2200/20110722020429843T,m-protein,Undergraduate lower division 13-14,Education,antibody,strep infection,b-cell

    Language:

    English

    Access Privileges:

    Public - Available to anyone

    License Deed:

    Creative Commons Attribution Non-Commercial Share Alike

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