Type:

Other

Description:

Porosomes, the universal secretory machinery at the cell plasma membrane, are cup-shaped supramolecular lipoprotein structures, where membrane-bound vesicles transiently dock and fuse to release intravesicular contents during cell secretion. In this review, the discovery of the porosome and its structure, dynamics, composition, and functional reconstitution are outlined. Furthermore, the architecture of porosome-like structures such as the "canaliculi system" in human platelets and various associated structures such as the T-bars at the Drosophila synapse or the "beams," "ribs," and "pegs" at the frog neuromuscular junction, each organized to facilitate a certain specialized secretory activity, are briefly discussed.

Subjects:

    Education Levels:

      Keywords:

      Content/background information,NSDL,NSDL_SetSpec_BEN,oai:nsdl.org:2200/20110722024238172T,Lipoprotein,Secretion,Life Science

      Language:

      English

      Access Privileges:

      Public - Available to anyone

      License Deed:

      Creative Commons Attribution Non-Commercial Share Alike

      Collections:

      None
      This resource has not yet been aligned.
      Curriki Rating
      'NR' - This resource has not been rated
      NR
      'NR' - This resource has not been rated

      This resource has not yet been reviewed.

      Not Rated Yet.

      Non-profit Tax ID # 203478467