The resource has been added to your collection
Access to the article is free, however registration and sign-in are required. Signaling by cell surface receptors and heterotrimeric guanine nucleotideâbinding proteins (G proteins) is one of the most exhaustively studied processes in the cell but remains a major focus of molecular pharmacology research. The pheromone-response system in yeast (see the Connections Map at Science's Signal Transduction Knowledge Environment) has provided numerous major advances in our understanding of G protein signaling and regulation. However, the basic features of this prototypical pathway have remained largely unchanged since the mid-1990s. New tools available in yeast are beginning to uncover new pathway components and interactions and have revealed signaling in unexpected locations within the cell.
This resource has not yet been reviewed.
Not Rated Yet.