In this problem space, you will have access to the following materials: * background information on HIV/AIDS, * the original Markham et al. reference and other primary literature, * viral sequences from each visit of each patient, * patients' CD4 counts at each visit, * phylogenetic trees of the virus sequences from each patient, * a phylogenetic tree of each patient's starting consensus viral sequence, * a published activity using this data from the book Microbes Count!, * and additional materials prepared by other users of the problem space.You can use this data to explore a number of different questions. Here are a few general questions to get you started: * Does the virus evolve the same way in different patients? * Are there any specific mutations that cause rapid immune decline? * What types of natural selection might be influencing HIV evolution? * Is HIV being transmitted between patients after initial infection?


  • Education > General

Education Levels:


    NSDL,Learn,Learner,Lesson plan,Audio/Visual,Social Sciences,oai:nsdl.org:2200/20110722014341839T,Public health,Hematology,Epidemiology,Phylogeny,Life Science,Teach,Teacher,Experiment/Lab Activity,Lesson/Lesson Plan,Immunology,NSDL_SetSpec_BEN,Virology,Laboratory exercise,Instructional Material,Human Biology,Structural biology,Undergraduate lower division 13-14,Evolutionary Biology,Teaching strategies & guidelines,Bioinformatics Genomics & Proteomics,Image,Image/Image Set,Education,Undergraduate upper division 15-16



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