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This case study was developed to complement the study of the immune system and to emphasize the crosstalk that occurs at the cellular level between B and T cells for proper immune system function. In reading the story of a young couple trying to understand the cause of their infant boy’s constant bacterial infections, students review the different classes of antibodies, their specific functions, and how they arise through isotope switching. In addition, students apply their knowledge of basic genetics as they examine how X-linked disorders are passed along and the role of genetic counselors in medicine.
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