This centers-based lesson on integers is designed for two-days of 45-minute lessons or one-day of a 90-minute lesson block. The lesson provides differentiated instruction using the H.O.P. Centers Framework. H.O.P. stands for Hands-On, Open-Ended, and Practice which are the themes for each of the three centers in the framework. Lesson structure is designed using brain research principles. In this lesson students will learn how to locate integers on a number line with a short engaging lesson, hands-on activity in which students use their sense of smell to sort numbers on a number line, practice writing about a word problem using integers, and engage in tiered practice of the concept.