Type:

Other

Description:

Interleukin-4 (IL-4) is a cytokine produced by TH2 type helper T cells and by mast cells, basophils, and eosinophils. This cytokine can elicit many responses, some of which are associated with allergy and asthma. Studies with long-term cell lines and primary cells have revealed differences in the signaling between these two experimental systems. Understanding these differences is important because therapeutic strategies targeting IL-4 and its signaling pathways are currently being tested to treat allergy and asthma.

Subjects:

  • Education > General

Education Levels:

    Keywords:

    oai:nsdl.org:2200/20080618215950791T,cytokine,NSDL,NSDL_SetSpec_BEN,signal transduction,T cell,Janus kinases,database,Connections Map,signaling pathway,Life Science,asthma,Education,Computing and Information

    Language:

    English

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    Public - Available to anyone

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    Creative Commons Attribution Non-Commercial Share Alike

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