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This teaching resource was developed by a K-12 science teacher in the American Physiological SocietyÂs 2008 Frontiers in Physiology Program. For more information on this program, please visit www.frontiersinphys.org. The purpose of this activity is to explain how a human karyotype is used to identify specific genetic disorders. During this lab students will research new treatments, the inheritance, diagnosis, and their application to biology, and symptoms or complications of a specific genetic disorder. Also, students will hypothesize what will happen to the frequencies of two alleles as a result of the presence of malaria in a population. Students should already have prior knowledge of the use of a pedigree and the similarities and differences of sex chromosomes and autosomes. Upon completion of this activity, students will be able to: identify chromosome pairs based upon band patterns and location of centromere and observe how selective forces can change allele frequencies in a population and cause evolution to occur.
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