Type:

Other

Description:

Access to the article is free, however registration and sign-in are required. Insects use a variety of strategies to fight pathogens at different stages of infection, which may guide antimicrobial development for human use.Two recent studies have quietly and subversively broken the models we've used to describe insect immunity. Impressively, they've accomplished this by using gross observational studies rather than mechanistic approaches. Haine et al. suggest that what we've considered the central pillar of insect immunity--antimicrobial peptides--may perform a "mopping up" role in clearing pathogens. Hedges et al. show that heritable epigenetic properties can have as large an impact on insect immunity as any genetically encoded pathway yet tested. Both studies teach us important lessons about the way a host organism interacts with microbes and may have immediate practical applications.

Subjects:

    Education Levels:

      Keywords:

      antimicrobial peptides,epigenetics,Toll pathway,NSDL_SetSpec_BEN,microbiota,Wolbachia,oai:nsdl.org:2200/20110722030239814T,NSDL

      Language:

      English

      Access Privileges:

      Public - Available to anyone

      License Deed:

      Creative Commons Attribution Non-Commercial Share Alike

      Collections:

      None
      This resource has not yet been aligned.
      Curriki Rating
      'NR' - This resource has not been rated
      NR
      'NR' - This resource has not been rated

      This resource has not yet been reviewed.

      Not Rated Yet.

      Non-profit Tax ID # 203478467