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Other

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Access to the article is free, however registration and sign-in are required. In response to genotoxic stresses that damage DNA, cells halt at a series of checkpoints during the cell cycle to provide sufficient time for the DNA to be repaired. In a Perspective, Sagata discusses a new study published elsewhere that shows how the kinase Chk1 contributes to S and G2 checkpoints by phosphorylating a key checkpoint phosphatase, Cdc25A.

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      Keywords:

      NSDL,NSDL_SetSpec_BEN,signaling pathways,regulation,cyclin-dependent kinases (CDKs),cell cycle checkpoints,Life Science,oai:nsdl.org:2200/20110722030400563T

      Language:

      English

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      Public - Available to anyone

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      Creative Commons Attribution Non-Commercial Share Alike

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