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Access to the article is free, however registration and sign-in are required. When a muscle contracts, it does so all at once and suddenly. Marx et al. (p. 818) show that one of the coordinated events underlying this simultaneous tensing is the release of calcium into the cytoplasm of the muscle cell. In their Perspective, Bers and Fill describe how ryanodine receptors, which release the calcium, act together to instantly raise the amount of calcium in the cytoplasm to a very high level, triggering a strong contraction of the muscle.

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      Keywords:

      sarcoplasmic reticulum (SR),coordinated-gating hypothesis,skeletal muscles,NSDL_SetSpec_BEN,oai:nsdl.org:2200/20110722030214505T,calcium,Life Science,stochastic-gating theory,NSDL

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      English

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      Creative Commons Attribution Non-Commercial Share Alike

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