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The operon model was proposed by Jacob, Monod, and Wollman based on studies on lactose-requiring mutations of E. coli. In this problem set you will work with the types of genetic and biochemical information used to unravel the inner workings of the lac operator-repressor regulation system.<p/> Instructions: The following problems have multiple choice answers. Correct answers are reinforced with a brief explanation. Incorrect answers are linked to tutorials to help solve the problem. <p/> <p>1. Components of the lac operon of E. coli</p> <p>2. The role of the inducer of the lac operon</p> <p>3. Phenotype of lac Z- E. coli cells</p> <p>4. Exchange of genetic information between bacteria</p> <p>5. DNA transfer by an F factor</p> <p>6. Different alleles for a bacterial genes</p> <p>7. Regulation of lac Z gene on an F' episome</p> <p>8. The Oc mutation of the lac operon</p> <p>9. Phenotype of lac I- cells</p> <p>10. Phenotype of cells diploid for lac I gene</p> <p>11. The effect of high glucose on lac operon expression</p> <p>12. Effect of high glucose concentrations</p> <p>13. Effect of high lactose and low glucose on lac operon</p> <p>14. Effect of the absence of glucose</p> <p/> <p>This resource is part of the <b><a href="http://www.curriki.org/xwiki/bin/view/Coll_ALoom/BiologyLinksforOLPC"> Biology Links for One Laptop Per Child</a></b> course which contains units on Exploring Life; The Cell; Genetics; Mechanisms of Evolution; The Evolutionary History of Biological Diversity; Plant Form and Function; Animal Form and Function; Ecology; and Astrobiology. </p>
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