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Other

Description:

The presenilins in combination with other proteins generate different -secretases, which are involved in the regulated intramembrane proteolysis of a variety of proteins. Understanding the specificity and regulation of these proteases will potentially lead to novel therapeutics for Alzheimer’s disease and cancer. Presenilins appear also to exert additional functions outside of the -secretase quartets, which needs further investigation.

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      Keywords:

      Content/background information,NSDL,NSDL_SetSpec_BEN,Geoscience,Life Science,oai:nsdl.org:2200/20110722031508372T,Cleavage,Physiology

      Language:

      English

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      Public - Available to anyone

      License Deed:

      Creative Commons Attribution Non-Commercial Share Alike

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