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These exercises use the QCP (Quantitative Circulatory Physiology) 2005 program which can be downloaded free from www.biosim.com. It is a simulation based on mathematical modeling of interactions between human body systemsÂ parameters. There are two objectives of the exercise. First to simulate the effects of increased inspired carbon dioxide levels on respiration rate, arterial and venous carbon dioxide partial pressure, arterial and venous bicarbonate concentration, and arterial and venous pH. Secondly to simulate the acute effects of changes in surface area, membrane thickness, lung collapse, and altitude on the previously named parameters with additional ones including oxygen saturation, arterial partial pressure of oxygen, ventilation, and tidal volume. In the first exercise of the procedure the student uses the QCP program to change the amount of inspired carbon dioxide inhaled by a simulated patient. They note the parameter values over a given interval of time by completing a data table. This is also done in the second exercise with a different data table. Questions are posed which require interpretation of data collected.
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