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Access to the article is free, however registration and sign-in are required. MAPKs are involved in many cellular processes such as cell survival, chromatin remodeling, and cell division. Nebreda and Gavin discuss new findings showing that the downstream effectors of MAPK activity are the Rsk protein kinases that can phosphorylate transcription factors, histones, and kinases involved in the cell cycle (Bhatt and Ferrell, Bonni et al., Gross et al.).
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