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Other

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Access to the article is free, however registration and sign-in are required. How do signaling networks within cells communicate with each other in order to respond to a vast array of external stimuli with the correct responses? In their Perspective, Ingolia and Murray discuss a new approach (Bhalla et al.) that elucidates the regulation of the MAPK signaling cascade in cultured cells and how cellular history contributes to this regulation.

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      Keywords:

      cellular circuits,cellular signaling networks,NSDL,NSDL_SetSpec_BEN,feedback loops,Mitogen-activated protein kinase (MAPK) cascades,signaling pathways,oai:nsdl.org:2200/20110722023116441T,Life Science,platelet-derived growth factor (PDGF)

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      English

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      Creative Commons Attribution Non-Commercial Share Alike

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