The resource has been added to your collection
Access to the article is free, however registration and sign-in are required. The assembly of actin filaments through the polymerization of actin monomers must be fine-tuned by the cell. In a Perspective, De La Cruz and Pollard explain exciting new findings (Otterbein et al.) showing that ATP hydrolysis and release of a phosphate group results in one segment of actin switching from a strand to a helical conformation. This conformation change favors the interaction of certain regulatory proteins--which regulate both actin polymerization and filament disassembly--with actin monomers and filaments.
This resource has not yet been reviewed.
Not Rated Yet.