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Access to the article is free, however registration and sign-in are required. The crystal structure of a membrane transporter protein sheds light on the molecular mechanism by which glucose is absorbed by the intestine and the kidneys. In order to benefit from ingested carbohydrates, they must first be broken down into simple sugars, such as glucose, and absorbed through the epithelial cells of the intestine. The glucose must then be reabsorbed in the kidneys. On page 810 of this issue, Faham et al. (1) report a major advance in elucidating the molecular mechanism by which this highly effective absorption is realized.
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