Type:

Other

Description:

Access to the article is free, however registration and sign-in are required. Cells produce a variety of ABC transporter proteins that shuttle numerous molecules across the plasma membrane so as to maintain the integrity of the intracellular milieu. As Higgins and Linton discuss in their Perspective, the first high-resolution crystal structure of one of these intricate ABC transporters has now been obtained (Chang and Roth). As the Perspective authors note, although the structure confirms much of the existing biochemical evidence, it also yields some interesting surprises that it will take much more analysis to explain.

Subjects:

    Education Levels:

      Keywords:

      membrane proteins,oai:nsdl.org:2200/20110722030756936T,protein structure,NSDL,NSDL_SetSpec_BEN,P-glycoprotein,ABC (ATP-binding cassette) transporters,transmembrane pathway,Life Science

      Language:

      English

      Access Privileges:

      Public - Available to anyone

      License Deed:

      Creative Commons Attribution Non-Commercial Share Alike

      Collections:

      None
      This resource has not yet been aligned.
      Curriki Rating
      'NR' - This resource has not been rated
      NR
      'NR' - This resource has not been rated

      This resource has not yet been reviewed.

      Not Rated Yet.

      Non-profit Tax ID # 203478467