Appropriate for high school students, this animation shows how scientists can determine the sequence of bases in human DNA. The animation provides an overview of the many steps involved in a sequencing method called the map-based shotgun approach. As the animation points out, there are other methods for sequencing and other variations on the approach shown here. There are five parts to the animation, and students use control buttons to navigate through it. The animation emphasizes that scientists currently cannot sequence an entire chromosome at once. Instead, they deal with overlapping, short lengths of DNA and work backwards to determine the sequence of a chromosome. Copyright 2005 Eisenhower National Clearinghouse


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