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Access to the article is free, however registration and sign-in are required. When a virus infects a cell, cellular defense mechanisms are activated, sometimes even causing cell death in an effort to stem the infection. As McFadden explains in his commentary, the virus in turn marshals its own countermeasures, striving to keep the cell alive so the virus can replicate and spread. A report by Schisler et al. shows how one of these countermeasures--synthesis of glutathione synthase, which protects cells against oxidative damage--is used by molluscum contagiosum virus and synthesized by a unique translation control mechanism for selenoproteins.
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