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Access to the article is free, however registration and sign-in are required. There may be drugs and a useful vaccine available to combat the hepatitis B virus, but one aspect of this pathogen remains a puzzle: the function of its HBx protein. As Ganem reveals in his Perspective, new findings (Bouchard et al.) show that this versatile viral protein is an activator of calcium-dependent Ras signaling, an observation that may explain many of its biological effects.

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      Keywords:

      hepatitis B virus (HBV),NSDL,NSDL_SetSpec_BEN,oai:nsdl.org:2200/20110722031011613T,signaling cascades,activation of Ras,HBx,open reading frames (ORFs),Pyk2 activation

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      English

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      Creative Commons Attribution Non-Commercial Share Alike

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